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Article

Distribution of recombination crossovers and the origin of haplotype blocks: the interplay of population history, recombination, and mutation.

American journal of human genetics - 1 Nov 2002

Wang Ning, Akey Joshua M, Zhang Kun, Chakraborty Ranajit, Jin Li

Abstract excerpt

Recent studies suggest that haplotypes are arranged into discrete blocklike structures throughout the human genome. Here, we present an alternative haplotype block definition that assumes no recombination within each block but allows for recombination between blocks, and we use it to study the combined effects of demographic history and various population genetic parameters on haplotype block characteristics....

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Identifiers

PMID: 12384857
DOI: 10.1086/344398
PMCID: PMC385104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Distribution of recombination crossovers and the origin of haplotype blocks: the interplay of population history, recombination, and mutation.PMID 12384857Read ↗

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