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Mupirocin-Induced Mutations in <i>ileS</i> in Various Genetic Backgrounds of Methicillin-Resistant Staphylococcus aureus

14 Aug 2014

Abstract excerpt

Topical mupirocin is widely used for the decolonization of methicillin-resistant Staphylococcus aureus (MRSA) carriers. We evaluated the capacity of various MRSA clonotypes to develop mutations in the ileS gene associated with low-level mupirocin resistance. Twenty-four mupirocin-sensitive MRSA isolates from a variety of genotypes (determined by a multilocus variable-number tandem-repeat assay) were selected....

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PMID: 25122856
DOI: 10.1128/jcm.01010-14

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