Article
Functional connectivity between tRNA binding domains in glutaminyl-tRNA synthetase.
Journal of molecular biology - 15 Mar 1996
Sherman J M, Thomann H U, Söll D
Abstract excerpt
The structure of Escherichia coli glutaminyl-tRNA synthetase (GlnRS) in complex with tRNAGln and ATP has identified a number a sequence-specific protein-tRNA interactions. The contribution to glutamine identity has previously been determined for the nucleotides in tRNAGln. Here, we report the mutational analysis of residues in all three tRNA recognition domains of GlnRS, thus completing a survey of the major...
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