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Article

A chimaeric glutamyl:glutaminyl-tRNA synthetase: implications for evolution.

The Biochemical journal - 15 Jan 2009

Saha Rajesh, Dasgupta Saumya, Basu Gautam, Roy Siddhartha

Abstract excerpt

aaRSs (aminoacyl-tRNA synthetases) are multi-domain proteins that have evolved by domain acquisition. The anti-codon binding domain was added to the more ancient catalytic domain during aaRS evolution. Unlike in eukaryotes, the anti-codon binding domains of GluRS (glutamyl-tRNA synthetase) and GlnRS (glutaminyl-tRNA synthetase) in bacteria are structurally distinct. This originates from the unique evolutionary...

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PMID: 18817520
DOI: 10.1042/BJ20080747

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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