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Article

Anticodon recognition and discrimination by the alpha-helix cage domain of class I lysyl-tRNA synthetase.

Biochemistry - 2 Oct 2007

Levengood Jeffrey D, Roy Hervé, Ishitani Ryuichiro, Söll Dieter, Nureki Osamu, Ibba Michael

Abstract excerpt

Aminoacyl-tRNA synthetases are normally found in one of two mutually exclusive structural classes, the only known exception being lysyl-tRNA synthetase which exists in both classes I (LysRS1) and II (LysRS2). Differences in tRNA acceptor stem recognition between LysRS1 and LysRS2 do not drastically impact cellular aminoacylation levels, focusing attention on the mechanism of tRNA anticodon recognition by LysRS1....

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Source

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Identifiers

PMID: 17760422
DOI: 10.1021/bi700815a
PMCID: PMC2583228

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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