Article
The eyeless mouse mutation (ey1) removes an alternative start codon from the Rx/rax homeobox gene.
Genesis (New York, N.Y. : 2000) - 1 Sept 2001
Tucker P, Laemle L, Munson A, Kanekar S, Oliver E R, Brown N, Schlecht H, Vetter M, Glaser T
Abstract excerpt
The eyeless inbred mouse strain ZRDCT has long served as a spontaneous model for human anophthalmia and the evolutionary reduction of eyes that has occurred in some naturally blind mammals. ZRDCT mice have orbits but lack eyes and optic tracts and have hypothalamic abnormalities. Segregation data suggest that a small number of interacting genes are responsible, including at least one major recessive locus, ey1....
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