Article
E-selectin genetic variation as a susceptibility factor for ischemic stroke.
Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2009
Haidari Mehran, Hajilooi Mehrdad, Rafiei Ali Reza, Rezaii Ali Akbar, Hoseinipanah Seyed Mohamad
Abstract excerpt
The polymorphism of the E-selectin gene has been implicated in the pathogenesis of atherosclerosis. We sought to explore whether the allelic variants relate to ischemic stroke. We conducted a case-control study of 359 cases of ischemic stroke and 353 community controls. Participants were evaluated for known cerebrovascular risk factors, and the E-selectin S128R and L554F genotypes were established using the...
Topics
- Aged
- Aged, 80 and over
- Case-Control Studies
- E-Selectin
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Middle Aged
