Article
The Ser128Arg polymorphism for E-selectin gene and brucellosis.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2007
Rafiei Alireza, Hajilooi Mehrdad, Vahedi Mohammad, Shakib Reza Jafari
Abstract excerpt
BACKGROUND: E-selectin is expressed on activated endothelial cells and plays an important role in regulating the early steps of tethering and rolling of leukocytes into and within sites of infection and inflammation. An A/C polymorphism (Ser128Arg) has been descried to alter ligand binding function. Therefore, the purpose of this case-control association study was to determine whether E-selectin polymorphism...
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