Article
Primary biliary cirrhosis: does X mark the spot?
Autoimmunity reviews - 1 Nov 2004
Selmi Carlo, Invernizzi Pietro, Miozzo Monica, Podda Mauro, Gershwin M Eric
Abstract excerpt
Primary biliary cirrhosis (PBC) is an autoimmune disease of unknown etiology leading to progressive destruction of intrahepatic bile duct, with cholestasis, cirrhosis, and eventually liver failure. Epidemiological data indicate that environmental factors trigger autoimmunity in genetically susceptible individuals, although no definitive association of PBC with specific genes has been found. Further, no convincing...
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