[Genetics of primary biliary cirrhosis].

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Article

[Genetics of primary biliary cirrhosis].

Orvosi hetilap - 16 Oct 2005

Hagymási Krisztina, Tulassay Zsolt

Abstract excerpt

The primary biliary cirrhosis is a chronic cholestatic liver disease, which is characterised by non-suppurative destruction of interlobular bile ducts. The precise etiopathogenesis of primary biliary cirrhosis remains unknown. Evidence suggest that genetic and environmental factors seem to be important. It shows strong heritability according to familial occurrence and monozygotic twins concordance. There is an...

Topics

ATP-Binding Cassette Transporters
Antigens, CD
Antigens, Differentiation
Apolipoproteins E
CTLA-4 Antigen
Chemokines
Chromosomes, Human, X
Cytokines
Female
Genes, MHC Class I
Genes, MHC Class II
Genetic Predisposition to Disease
Humans
Interleukin-1
Interleukin-10
Liver Cirrhosis, Biliary
Major Histocompatibility Complex
Male

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PMID: 16315996

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