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Article

X Chromosome Monosomy: A Common Mechanism for Autoimmune Diseases

1 Jul 2005

Abstract excerpt

The majority of human autoimmune diseases are characterized by female predominance. Although sex hormone influences have been suggested to explain this phenomenon, the mechanism remains unclear. In contrast to the role of hormones, it has been suggested, based on pilot data in primary biliary cirrhosis, that there is an elevation of monosomy X in autoimmune disease. Using peripheral white blood cells from women...

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Identifiers

PMID: 15972694
DOI: 10.4049/jimmunol.175.1.575

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Source receipt: pubmed, retrieved 7 Sept 2026.

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