Article
Epigenetics and Primary Biliary Cirrhosis: a Comprehensive Review and Implications for Autoimmunity.
Clinical reviews in allergy & immunology - 1 Jun 2016
Xie Yu-Qing, Ma Hong-Di, Lian Zhe-Xiong
Abstract excerpt
Primary biliary cirrhosis (PBC) is a chronic inflammatory autoimmune disease that develops based upon the interaction of genetic and environmental factors. Recent genome-wide association studies (GWAS) have identified dozens of predisposing variants including HLA, IL12A, and CTLA4 but have been d...
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