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Article

Deleterious mutations in animal mitochondrial DNA.

Genetica - 1 Jan 1998

Nachman M W

Abstract excerpt

A simple neutral model predicts that the ratio of non-synonymous to synonymous fixed differences between species will be the same as the ratio of non-synonymous to synonymous polymorphisms within species. This prediction is tested with existing mitochondrial datasets from 25 animal species. In slightly over half of the studies, the ratio of replacement to silent polymorphisms within species is significantly...

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PMID: 9720272

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