Article
Prevalence of positive selection among nearly neutral amino acid replacements in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America - 17 Apr 2007
Sawyer Stanley A, Parsch John, Zhang Zhi, Hartl Daniel L
Abstract excerpt
We have estimated the selective effects of amino acid replacements in natural populations by comparing levels of polymorphism in 91 genes in African populations of Drosophila melanogaster with their divergence from Drosophila simulans. The genes include about equal numbers whose level of expression in adults is greater in males, greater in females, or approximately equal in the sexes. Markov chain Monte Carlo...
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