Article
The temporal dynamics of slightly deleterious mutations in Escherichia coli and Shigella spp.
Molecular biology and evolution - 1 Feb 2009
Balbi Kevin J, Rocha Eduardo P C, Feil Edward J
Abstract excerpt
The Shigella are recently emerged clones of Escherichia coli, which have independently adopted an intracellular pathogenic lifestyle. We examined the molecular evolutionary consequences of this niche specialization by comparing the normalized, directional frequency profiles of unique polymorphisms within 2,098 orthologues representing the intersection of five E. coli and four Shigella genomes. We note a surfeit...
Topics
- Base Composition
- Escherichia coli
- Genome, Bacterial
- Mutation
- Principal Component Analysis
- Shigella
- Shigella sonnei