Article

From individuals to ancestries: towards attributing trait variation to haplotypes

2025-03-14

Abstract excerpt

Genome-wide association studies (GWAS) have revolutionized our understanding of the genetic basis of complex traits and diseases, but limitations in SNP-centric approaches to population stratification limit the resolution of fine-scale population structures. Here we consider the use of haplotypes to represent population structure, leveraging haplotype components (HCs) for an improved understanding of trait associa...

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Literature Corpus work: cfeacad9-4284-5b72-b543-b227a219fc5d
DOI: 10.1101/2025.03.13.25323895

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