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Article

The story of the serpin plasminogen activator inhibitor 1: is there any need for another mutant?

Thrombosis and haemostasis - 1 Nov 2004

De Taeye Bart, Gils Ann, Declerck Paul J

Abstract excerpt

The importance of obtaining insight in the structure/function relationship in the serpin plasminogen activator inhibitor type-1 can be understood from the major role PAI-1 plays in different (patho)physiological processes, mainly because of its involvement in the plasminogen/plasmin system. Moreover, during the past years, studies indicated a contribution of PAI-1 to the development of cardiovascular disease in...

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Identifiers

PMID: 15543316
DOI: 10.1160/TH04-05-0269

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The story of the serpin plasminogen activator inhibitor 1: is there any need for another mutant?PMID 15543316Read ↗

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Remarkable extension of PAI-1 half-life surprisingly brings no changes to its structure.Semantic proximity Read ↗

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