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Article

Stability and Lability of Parental Methylation Imprints in Development and Disease.

Genes - 2 Dec 2019

Farhadova Sabina, Gomez-Velazquez Melisa, Feil Robert

Abstract excerpt

DNA methylation plays essential roles in mammals. Of particular interest are parental methylation marks that originate from the oocyte or the sperm, and bring about mono-allelic gene expression at defined chromosomal regions. The remarkable somatic stability of these parental imprints in the pre-implantation embryo-where they resist global waves of DNA demethylation-is not fully understood despite the importance...

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Identifiers

PMID: 31810366
DOI: 10.3390/genes10120999
PMCID: PMC6947649

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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