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Article

Gene-specific timing and epigenetic memory in oocyte imprinting

3 Mar 2004

Abstract excerpt

Imprinted genes are differentially marked during germ cell development to allow for their eventual parent-of-origin specific expression. A subset of imprinted genes becomes methylated during oocyte growth in both mouse and human. However the timing and mechanisms of methylation acquisition are unknown. Here, we examined the methylation of the Snrpn, Igf2r, Peg1 and Peg3 differentially methylated regions in...

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Share to Epigenetics and DNA Methylation
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PMID: 14998934
DOI: 10.1093/hmg/ddh104

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