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Role of the Dnmt3 family in de novo methylation of imprinted and repetitive sequences during male germ cell development in the mouse

6 Jul 2007

Abstract excerpt

DNA methylation is an important epigenetic modification regulating various biological phenomena, including genomic imprinting and transposon silencing. It is known that methylation of the differentially methylated regions (DMRs) associated with paternally imprinted genes and of some repetitive elements occurs during male germ cell development in the mouse. We have performed a detailed methylation analysis of the...

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PMID: 17616512
DOI: 10.1093/hmg/ddm179

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Role of the Dnmt3 family in de novo methylation of imprinted and repetitive sequences during male germ cell development in the mousePMID 17616512Read ↗

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<i>rahu</i> is a mutant allele of <i>Dnmt3c</i> , encoding a DNA methyltransferase homolog required for meiosis and transposon repression in the mouse male germlineSemantic proximity Read ↗

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rahu is a mutant allele of Dnmt3c, encoding a DNA methyltransferase homolog required for meiosis and transposon repression in the mouse male germline.Semantic proximity Read ↗

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