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Article

The insulin-like growth factor-II receptor gene is associated with type 1 diabetes: evidence of a maternal effect.

The Journal of clinical endocrinology and metabolism - 1 Nov 2004

McCann Jennifer A, Xu Yong Qin, Frechette Rosalie, Guazzarotti Laura, Polychronakos Constantin

Abstract excerpt

Susceptibility to type 1 diabetes (T1D) is a complex trait, involving several loci. One of these putative loci, insulin-dependent diabetes mellitus-8 (IDDM8) at 6q, has been found to be subject to parental effects, suggesting the involvement of an imprinted gene. IGF-II receptor (IGF2R), the best-studied imprinted gene in the IDDM8 region, encodes the IGF-2 receptor, a protein involved in many biological...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15531531
DOI: 10.1210/jc.2004-0553

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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