Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of two maternal transmission ratio distortion loci in pedigrees of the Framingham heart study.

Scientific reports - 1 Jan 2013

Liu Yang, Zhang Liangliang, Xu Shuhua, Hu Landian, Hurst Laurence D, Kong Xiangyin

Abstract excerpt

Transmission ratio distortion (TRD) is indicated by the recovery of alleles in offspring in non-Mendelian proportions. An assumption of Mendelian proportion is central to many methods to identify disease-associated markers. This seems reasonable as, while TRD cases have been occasionally observed in various species few instances have been identified in humans. Here we search for evidence of paternal or maternal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to TRD gene
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genomic Imprinting

Share to Heart Diseases

Share to Mothers

Share to Pedigree

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 23828458
DOI: 10.1038/srep02147
PMCID: PMC3701898

Genes

TRD
LRP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of two maternal transmission ratio distortion loci in pedigrees of the Framingham heart study.PMID 23828458Read ↗

A systematic review and critical analysis of the evidence for transmission ratio distortion in humans.Semantic proximity Read ↗

Evaluating the evidence for transmission distortion in human pedigrees.Semantic proximity Read ↗

Transmission ratio distortion: review of concept and implications for genetic association studies.Semantic proximity Read ↗

Unravelling transmission ratio distortion across the bovine genome: identification of candidate regions for reproduction defects.Semantic proximity Read ↗

Transmission ratio distortion in families from the Framingham Heart Study.Semantic proximity Read ↗

Distortion of Mendelian segregation across the Angus cattle genome uncovering regions affecting reproduction.Semantic proximity Read ↗

Bayesian analysis of parent-specific transmission ratio distortion in seven Spanish beef cattle breeds.Semantic proximity Read ↗

Discriminating between allele- and genotype-specific transmission ratio distortion.Semantic proximity Read ↗

Evidence for extensive transmission distortion in the human genome.Semantic proximity Read ↗

Discovering lethal alleles across the turkey genome using a transmission ratio distortion approach.Semantic proximity Read ↗

Genomic screening of allelic and genotypic transmission ratio distortion in horse.Semantic proximity Read ↗

Markers with low GenTrain scores can generate spurious signals in genome-wide scans for transmission ratio distortion.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.