Article
Altered transmission of maternal angiotensin II receptor haplotypes in fetal growth restriction.
Human mutation - 1 Feb 2006
Tower Clare, Chappell Sally, Acharya Meera, Crane Richard, Szolin Stephanie, Symonds Lyneth, Chevins Helen, Kalsheker Noor, Baker Philip, Morgan Linda
Abstract excerpt
Fetal growth restriction (FGR) predisposes to significant short- and long-term health problems. Epidemiological studies have suggested a role for inherited factors in its pathogenesis. The angiotensin II receptor genes, AGTR1 and AGTR2, are candidate genes because they mediate processes that are important for placentation. This study investigated AGTR1 and AGTR2 haplotypes and genotypes in FGR. A total of 107...
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