The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes.

doi:10.1038/ng.493

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes.

Nature genetics - 1 Jan 2010

Wallace Chris, Smyth Deborah J, Maisuria-Armer Meeta, Walker Neil M, Todd John A, Clayton David G

Abstract excerpt

Genome-wide association (GWA) studies to map common disease susceptibility loci have been hugely successful, with over 300 reproducibly associated loci reported to date. However, these studies have not yet provided convincing evidence for any susceptibility locus subject to parent-of-origin effects. Using imputation to extend existing GWA datasets, we have obtained robust evidence at rs941576 for paternally...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 14

Share to Diabetes Mellitus, Type 1

Share to Family Health

Share to Genomic Imprinting

Share to Intercellular Signaling Peptides and Proteins

Share to Meta-Analysis as Topic

Share to RNA, Long Noncoding

Source

Open in PubMed Open full text

Identifiers

PMID: 19966805
DOI: 10.1038/ng.493
PMCID: PMC2820243

Genes

DLK1
TYK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes.PMID 19966805Read ↗

A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci.Semantic proximity Read ↗

Shared genetic contribution to type 1 and type 2 diabetes riskSemantic proximity Read ↗

Identification of loci where DNA methylation potentially mediates genetic risk of type 1 diabetes.Semantic proximity Read ↗

A comprehensive reanalysis of publicly available GWAS datasets reveals an X chromosome rare regulatory variant associated with high risk for type 2 diabetesSemantic proximity Read ↗

Genetic and epigenetic factors in etiology of diabetes mellitus type 1.Semantic proximity Read ↗

Shared genetic risk contributes to type 1 and type 2 diabetes etiologySemantic proximity Read ↗

Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes.Semantic proximity Read ↗

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.Semantic proximity Read ↗

Whole-exome and Whole-genome Sequencing of 1097 Individuals with Type 1 Diabetes Reveals Novel Genes for Diabetic Kidney DiseaseSemantic proximity Read ↗

Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetesSemantic proximity Read ↗

The molecular genetics of type 1 diabetes: new genes and emerging mechanisms.Semantic proximity Read ↗

Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.