Article
Regulatory role of dADAR in ROS metabolism in Drosophila CNS.
Brain research. Molecular brain research - 24 Nov 2004
Chen Li, Rio Donald C, Haddad Gabriel G, Ma Enbo
Abstract excerpt
Pre-mRNA adenosine deaminase (ADAR) is involved in many physiological processes by either directly converting adenosine to inosine in certain pre-mRNAs or indirectly regulating expression of certain genes. Mutations of Drosophila ADAR (dADAR) results in neuronal dysfunction and hypersensitivity to oxygen deprivation. Recently, we found that the mutant flies were very resistant to paraquat, a compound that...
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