Article
Developmental expression and enzymatic activity of pre-mRNA deaminase in Drosophila melanogaster.
Brain research. Molecular brain research - 15 Jun 2002
Ma Enbo, Tucker Mary Catherine, Chen Qiaofang, Haddad Gabriel G
Abstract excerpt
Pre-mRNA editing, conducted by adenosine deaminase acting on RNA (ADAR), plays an important role in many biological/physiological processes. This post-transcriptional event creates protein diversity that stems from a single gene via alteration of either genetic codons or alternative splicing sites. Our data demonstrate that both expression of Drosophila ADAR (dADAR) gene and dADAR editing activity are highly...
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