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Article

Genetic approaches to studying adenosine-to-inosine RNA editing.

Methods in enzymology - 1 Jan 2007

Jepson James E C, Reenan Robert A

Abstract excerpt

Increasing proteomic diversity via the hydrolytic deamination of adenosine to inosine (A-to-I) in select mRNA templates appears crucial to the correct functioning of the nervous system in several model organisms, including Drosophila, Caenorabditis elegans, and mice. The genome of the fruitfly, Drosophila melanogaster, contains a single gene encoding the enzyme responsible for deamination, termed ADAR (for...

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Source

Identifiers

PMID: 17662845
DOI: 10.1016/S0076-6879(07)24012-1

Genes

ADAR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic approaches to studying adenosine-to-inosine RNA editing.PMID 17662845Read ↗

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The dsRBP and inactive editor ADR-1 utilizes dsRNA binding to regulate A-to-I RNA editing across the C. elegans transcriptome.Semantic proximity Read ↗

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