Article
Genome-wide association analysis of oxidative stress resistance in Drosophila melanogaster.
PloS one - 1 Jan 2012
Weber Allison L, Khan George F, Magwire Michael M, Tabor Crystal L, Mackay Trudy F C, Anholt Robert R H
Abstract excerpt
BACKGROUND: Aerobic organisms are susceptible to damage by reactive oxygen species. Oxidative stress resistance is a quantitative trait with population variation attributable to the interplay between genetic and environmental factors. Drosophila melanogaster provides an ideal system to study the genetics of variation for resistance to oxidative stress. METHODS AND FINDINGS: We used 167 wild-derived inbred lines...
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