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Article

Essential role of Duox in stabilization of Drosophila wing.

The Journal of biological chemistry - 23 Sept 2011

Anh Nguyen Thi Tu, Nishitani Maiko, Harada Shigeharu, Yamaguchi Masamitsu, Kamei Kaeko

Abstract excerpt

NADPH oxidase produces reactive oxygen species (ROS). Drosophila melanogaster has two homologs of NADPH oxidase, dNox and dDuox, with functions that remain unclear in vivo. To clarify these functions, two independent transgenic fly lines expressing dsRNA targeted for different portions of dDuox mRNA were used. In both flies, en-GAL4> UAS-dDuoxIR(976-1145) and en-GAL4> UAS-dDuoxIR(370-518), in which dDuox was...

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Identifiers

PMID: 21808060
DOI: 10.1074/jbc.M111.263178
PMCID: PMC3190906

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