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Article

The ADAR RNA editing enzyme controls neuronal excitability in Drosophila melanogaster.

Nucleic acids research - 1 Jan 2014

Li Xianghua, Overton Ian M, Baines Richard A, Keegan Liam P, O'Connell Mary A

Abstract excerpt

RNA editing by deamination of specific adenosine bases to inosines during pre-mRNA processing generates edited isoforms of proteins. Recoding RNA editing is more widespread in Drosophila than in vertebrates. Editing levels rise strongly at metamorphosis, and Adar(5G1) null mutant flies lack editing events in hundreds of CNS transcripts; mutant flies have reduced viability, severely defective locomotion and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24137011
DOI: 10.1093/nar/gkt909
PMCID: PMC3902911

Genes

ADAR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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