Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The haplotype structure of the human major histocompatibility complex.

Human immunology - 1 Jan 2000

Alper Chester A, Larsen Charles E, Dubey Devendra P, Awdeh Zuheir L, Fici Dolores A, Yunis Edmond J

Abstract excerpt

There is great interest in the use of single-nucleotide polymorphisms (SNPs) and linkage disequilibrium (LD) analysis to localize human disease genes. The results suggest that the human genome, including the major histocompatibility complex (MHC), consists largely of 5- to 200-kb blocks of sequen...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Major Histocompatibility Complex
Share to Chromosome Mapping
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Human

Share to Haplotypes

Share to Linkage Disequilibrium

Share to White People

Source

Identifiers

PMID: 16698428
DOI: 10.1016/j.humimm.2005.11.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16698428-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The haplotype structure of the human major histocompatibility complex.PMID 16698428Read ↗

Genetic fixity in the human major histocompatibility complex and block size diversity in the class I region including HLA-E.Semantic proximity Read ↗

The structure of haplotype blocks in the human genome.Semantic proximity Read ↗

High-resolution haplotype structure in the human genome.Semantic proximity Read ↗

Haplotype-specific linkage disequilibrium patterns define the genetic topography of the human MHC.Semantic proximity Read ↗

Intrahaplotypic Variants Differentiate Complex Linkage Disequilibrium within Human MHC Haplotypes.Semantic proximity Read ↗

A haplotype map of the human genome.Semantic proximity Read ↗

An integrated haplotype map of the human major histocompatibility complex.Semantic proximity Read ↗

Definition and clinical importance of haplotypes.Semantic proximity Read ↗

Pedigree-Defined Haplotypes and Their Applications to Genetic Studies.Semantic proximity Read ↗

A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC.Semantic proximity Read ↗

Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history.Semantic proximity Read ↗

What has GWAS done for HLA and disease associations?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.