Article
MucA-mediated coordination of type III secretion and alginate synthesis in Pseudomonas aeruginosa.
Journal of bacteriology - 1 Nov 2004
Wu Weihui, Badrane Hassan, Arora Shiwani, Baker Henry V, Jin Shouguang
Abstract excerpt
The type III secretion system (T3SS) of Pseudomonas aeruginosa is an important virulence factor. The T3SS of P. aeruginosa can be induced by a low calcium signal or upon direct contact with the host cells. The exact pathway of signal sensing and T3SS activation is not clear. By screening a transposon insertion mutant library of the PAK strain, mutation in the mucA gene was found to cause repression of T3SS...
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