Article
Pseudomonas aeruginosa in cystic fibrosis: role of mucC in the regulation of alginate production and stress sensitivity.
Microbiology (Reading, England) - 1 Nov 1997
Boucher J C, Schurr M J, Yu H, Rowen D W, Deretic V
Abstract excerpt
Alginate production in Pseudomonas aeruginosa and the associated mucoid phenotype of isolates from cystic fibrosis patients are under the control of the algU mucABCD cluster. This group of genes encodes AlgU, the P. aeruginosa equivalent of the extreme heat shock sigma factor sigma E in Gram-nega...
Topics
- Alginates
- Bacterial Proteins
- Cystic Fibrosis
- Gene Expression Regulation, Bacterial
- Glucuronic Acid
- Hexuronic Acids
- Hot Temperature
- Humans
- Mutagenesis, Insertional
- Mutation
- Osmolar Concentration
- Phenotype
- Pseudomonas aeruginosa
- Reactive Oxygen Species
- Sigma Factor
- Sodium Chloride