Article
Truncation of type IV pilin induces mucoidy in Pseudomonas aeruginosa strain PAO579.
MicrobiologyOpen - 1 Jun 2013
Ryan Withers T, Heath Damron F, Yin Yeshi, Yu Hongwei D
Abstract excerpt
Pseudomonas aeruginosa is a Gram negative, opportunistic pathogen that uses the overproduction of alginate, a surface polysaccharide, to form biofilms in vivo. Overproduction of alginate, also known as mucoidy, affords the bacterium protection from the host's defenses and facilitates the establishment of chronic lung infections in individuals with cystic fibrosis. Expression of the alginate biosynthetic operon is...
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