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Article

Alginate synthesis in Pseudomonas aeruginosa: environmental regulation of the algC promoter

1 Dec 1992

Abstract excerpt

The exopolysaccharide alginate is a major virulence factor of Pseudomonas aeruginosa strains that infect the lungs of cystic fibrosis patients. The synthesis of alginate is almost uniquely associated with the pathogenicity of P. aeruginosa within the environment of the cystic fibrosis lung. The gene algC is one of the essential alginate biosynthetic genes and codes for the enzyme phosphomannomutase. In this...

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PMID: 1447138
DOI: 10.1128/jb.174.23.7680-7688.1992

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alginate synthesis in Pseudomonas aeruginosa: environmental regulation of the algC promoterPMID 1447138Read ↗

Mucoid Pseudomonas aeruginosa in cystic fibrosis: mutations in the muc loci affect transcription of the algR and algD genes in response to environmental stimuli.Semantic proximity Read ↗

Pseudomonas aeruginosa in cystic fibrosis: role of mucC in the regulation of alginate production and stress sensitivity.Semantic proximity Read ↗

The Transcriptional Regulator AlgR Is Essential for Pseudomonas aeruginosa PathogenesisSemantic proximity Read ↗

Multiple promoters and induction by heat shock of the gene encoding the alternative sigma factor AlgU (sigma E) which controls mucoidy in cystic fibrosis isolates of Pseudomonas aeruginosa.Semantic proximity Read ↗

Analysis of promoters controlled by the putative sigma factor AlgU regulating conversion to mucoidy in Pseudomonas aeruginosa: relationship to sigma E and stress response.Semantic proximity Read ↗

Identification of the algZ gene upstream of the response regulator algR and its participation in control of alginate production in Pseudomonas aeruginosa.Semantic proximity Read ↗

Alginate-dependent gene expression mechanism in Sphingomonas sp. strain A1.Semantic proximity Read ↗

Transcriptional analysis of the Pseudomonas aeruginosa genes algR, algB, and algD reveals a hierarchy of alginate gene expression which is modulated by algT.Semantic proximity Read ↗

Deletion of algK in mucoid Pseudomonas aeruginosa blocks alginate polymer formation and results in uronic acid secretion.Semantic proximity Read ↗

Evidence for Sigma Factor Competition in the Regulation of Alginate Production by Pseudomonas aeruginosaSemantic proximity Read ↗

Genetic analysis of the alginate biosynthetic gene cluster of <i>Pseudomonas aeruginosa</i> shows evidence of an operonic structureSemantic proximity Read ↗

Outer-membrane protein LptD (PA0595) plays a role in the regulation of alginate synthesis in Pseudomonas aeruginosa.Semantic proximity Read ↗

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