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Biochemistry, function, and deficiency of vitamin B <sub>12</sub> in <i>Caenorhabditis elegans</i>

2 Aug 2016

Abstract excerpt

Caenorhabditis elegans is a nematode that has been widely used as an animal for investigation of diverse biological phenomena. Vitamin B12 is essential for the growth of this worm, which contains two cobalamin-dependent enzymes, methylmalonyl-CoA mutase and methionine synthase. A full complement of gene homologs encoding the enzymes associated with the mammalian intercellular metabolic processes of vitamin B12 is...

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PMID: 27486161
DOI: 10.1177/1535370216662713

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