Article
Thiamin pyrophosphokinase is required for thiamin cofactor activation in Arabidopsis.
Plant molecular biology - 1 Sept 2007
Ajjawi Imad, Rodriguez Milla Miguel A, Cushman John, Shintani David K
Abstract excerpt
Thiamin pyrophosphate (TPP) is an essential enzyme cofactor required for the viability of all organisms. Whether derived from exogenous sources or through de novo synthesis, thiamin must be pyrophosphorylated for cofactor activation. The enzyme thiamin pyrophosphokinase (TPK) catalyzes the conversion of free thiamin to TPP in plants and other eukaryotic organisms and is central to thiamin cofactor activation....
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