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Article

Cellular distribution and functions of wild-type and constitutively activated Dictyostelium PakB.

Molecular biology of the cell - 1 Jan 2005

de la Roche Marc, Mahasneh Amjad, Lee Sheu-Fen, Rivero Francisco, Côté Graham P

Abstract excerpt

Dictyostelium PakB, previously termed myosin I heavy chain kinase, is a member of the p21-activated kinase (PAK) family. Two-hybrid assays showed that PakB interacts with Dictyostelium Rac1a/b/c, RacA (a RhoBTB protein), RacB, RacC, and RacF1. Wild-type PakB displayed a cytosolic distribution with a modest enrichment at the leading edge of migrating cells and at macropinocytic and phagocytic cups, sites...

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Identifiers

PMID: 15509655
DOI: 10.1091/mbc.e04-06-0534
PMCID: PMC539168

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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