Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Recombination hotspots and block structure of linkage disequilibrium in the human genome exemplified by detailed analysis of PGM1 on 1p31.

Human molecular genetics - 15 Dec 2004

Rana Naheed A, Ebenezer Neil D, Webster Andrew R, Linares Andres R, Whitehouse David B, Povey Sue, Hardcastle Alison J

Abstract excerpt

The distribution of linkage disequilibrium (LD) in the human genome has important consequences for the design of experiments that infer susceptibility genes for complex disease using association studies. Recent studies have shown a non-random distribution of human meiotic recombination associated with intervening tracts of LD. Little is known about the processes, patterns and frequency of reciprocal meiotic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 1
Share to Genetic Markers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Human

Share to Haplotypes

Share to Linkage Disequilibrium

Share to Phosphoglucomutase

Share to Polymorphism, Single Nucleotide

Share to Recombination, Genetic

Source

Identifiers

PMID: 15509594
DOI: 10.1093/hmg/ddh337

Genes

PGM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Recombination hotspots and block structure of linkage disequilibrium in the human genome exemplified by detailed analysis of PGM1 on 1p31.PMID 15509594Read ↗

Systematic Analyses of Autosomal Recombination Rates from the 1000 Genomes Project Uncovers the Global Recombination Landscape in HumansSemantic proximity Read ↗

A high-resolution recombination map of the human genome.Semantic proximity Read ↗

Human recombination hot spots hidden in regions of strong marker association.Semantic proximity Read ↗

High-resolution mapping of crossovers reveals extensive variation in fine-scale recombination patterns among humans.Semantic proximity Read ↗

A haplotype map of the human genome.Semantic proximity Read ↗

A fine-scale map of recombination rates and hotspots across the human genome.Semantic proximity Read ↗

Evidence for substantial fine-scale variation in recombination rates across the human genome.Semantic proximity Read ↗

Polymorphism in the activity of human crossover hotspots independent of local DNA sequence variation.Semantic proximity Read ↗

Fine-scale recombination rate differences between sexes, populations and individuals.Semantic proximity Read ↗

A common sequence motif associated with recombination hot spots and genome instability in humans.Semantic proximity Read ↗

The fine-scale structure of recombination rate variation in the human genome.Semantic proximity Read ↗

A second generation human haplotype map of over 3.1 million SNPs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.