Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational analysis of TraM correlates oligomerization and DNA binding with autoregulation and conjugative DNA transfer.

The Journal of biological chemistry - 31 Dec 2004

Lu Jun, Zhao Wen, Frost Laura S

Abstract excerpt

F plasmid TraM, an autoregulatory homotetramer, is essential for F plasmid bacterial conjugative transfer, one of the major mechanisms for horizontal gene dissemination. TraM cooperatively binds to three sites (sbmA, -B, and -C) near the origin of transfer in the F plasmid. To examine whether or not tetramerization of TraM is required for autoregulation and F conjugation, we used a two-plasmid system to screen...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta-Galactosidase
Share to Chromatography
Share to Codon

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dimerization

Share to Electrophoresis, Polyacrylamide Gel

Share to F Factor

Share to Immunoblotting

Share to Oligonucleotides

Source

Identifiers

PMID: 15509578
DOI: 10.1074/jbc.M409352200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational analysis of TraM correlates oligomerization and DNA binding with autoregulation and conjugative DNA transfer.PMID 15509578Read ↗

A rapid screen for functional mutants of TraM, an autoregulatory protein required for F conjugation.Semantic proximity Read ↗

Mechanistic basis of plasmid-specific DNA binding of the F plasmid regulatory protein, TraM.Semantic proximity Read ↗

Structural basis of cooperative DNA recognition by the plasmid conjugation factor, TraM.Semantic proximity Read ↗

Characterization of the F-plasmid conjugative transfer gene traU.Semantic proximity Read ↗

TraM of plasmid R1 controls transfer gene expression as an integrated control element in a complex regulatory network.Semantic proximity Read ↗

Specific DNA recognition by F Factor TraY involves beta-sheet residues.Semantic proximity Read ↗

Characterization of the F plasmid mating aggregation gene traN and of a new F transfer region locus trbE.Semantic proximity Read ↗

Error-prone PCR mutagenesis reveals functional domains of a bacterial transcriptional activator, TraJ.Semantic proximity Read ↗

Protonation-mediated structural flexibility in the F conjugation regulatory protein, TraM.Semantic proximity Read ↗

Quorum-sensing antiactivator TraM forms a dimer that dissociates to inhibit TraR.Semantic proximity Read ↗

F plasmid TraF and TraH are components of an outer membrane complex involved in conjugation.Semantic proximity Read ↗

TraY DNA recognition of its two F factor binding sites.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.