Article
TraM of plasmid R1 controls transfer gene expression as an integrated control element in a complex regulatory network.
Molecular microbiology - 1 Aug 1997
Pölzleitner E, Zechner E L, Renner W, Fratte R, Jauk B, Högenauer G, Koraimann G
Abstract excerpt
Site-directed mutagenesis was used to investigate the functions of the traM gene in plasmid R1-mediated bacterial conjugation. Three mutant alleles, a null mutation, a sense mutation and a stop mutation, were recombined back into the R1-16 plasmid, a transfer-derepressed (finO-) variant of plasmid R1. The frequency of conjugative transfer of the traM null mutant derivative of R1-16 was 10(7)-fold lower than that...
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