Article
Mechanistic basis of plasmid-specific DNA binding of the F plasmid regulatory protein, TraM.
Journal of molecular biology - 11 Nov 2014
Peng Yun, Lu Jun, Wong Joyce J W, Edwards Ross A, Frost Laura S, Mark Glover J N
Abstract excerpt
The conjugative transfer of bacterial F plasmids relies on TraM, a plasmid-encoded protein that recognizes multiple DNA sites to recruit the plasmid to the conjugative pore. In spite of the high degree of amino acid sequence conservation between TraM proteins, many of these proteins have markedly different DNA binding specificities that ensure the selective recruitment of a plasmid to its cognate pore. Here we...
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