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Article

Murine cytomegalovirus with a transposon insertional mutation at open reading frame M35 is defective in growth in vivo.

Journal of virology - 1 Jul 2003

Tam Ada, Zhu Jiaming, Hai Rong, Haghjoo Erik, Tong Tuong, Zhan Xiaoyan, Lu Sangwei, Liu Fenyong

Abstract excerpt

We had previously constructed a pool of murine cytomegalovirus (MCMV) mutants that contained a Tn3-based transposon sequence randomly inserted in the viral genome. In the study reported here, one of the mutants, RvM35, which contains the transposon insertion at open reading frame M35, was characterized both in vitro in tissue cultures and in immunocompetent Balb/c and immunodeficient SCID mice. Our results...

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Identifiers

PMID: 12829814
DOI: 10.1128/jvi.77.14.7746-7755.2003
PMCID: PMC161956

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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