Article
Forward with BACs: new tools for herpesvirus genomics.
Trends in genetics : TIG - 1 Jun 2000
Brune W, Messerle M, Koszinowski U H
Abstract excerpt
The large, complex genomes of herpesviruses document the high degree of adaptation of these viruses to their hosts. Not surprisingly, the methods developed over the past 30 years to analyse herpesvirus genomes have paralleled those used to investigate the genetics of eukaryotic cells. The recent use of bacterial artificial chromosome (BAC) technology in herpesvirus genetics has made their genomes accessible to...
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