Article
Improving baculovirus recombination.
Nucleic acids research - 15 Jan 2003
Zhao Yuguang, Chapman David A G, Jones Ian M
Abstract excerpt
Recombinant baculoviruses have established themselves as a favoured technology for the high-level expression of recombinant proteins. The construction of recombinant viruses, however, is a time consuming step that restricts consideration of the technology for high throughput developments. Here we use a targeted gene knockout technology to inactivate an essential viral gene that lies adjacent to the locus used for...
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