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Article

Characterization of virus-specific CD8(+) effector T cells in the course of HIV-1 infection: longitudinal analyses in slow and rapid progressors.

Clinical immunology (Orlando, Fla.) - 1 Dec 2004

Jansen Christine A, Piriou Erwan, Bronke Corine, Vingerhoed José, Kostense Stefan, van Baarle Debbie, Miedema Frank

Abstract excerpt

Studies in humans have provided evidence that CD8(+) T cells exhibit distinct phenotypical and functional properties dependent on virus specificity. It is not known how these T-cell phenotypes develop over the course of infection. Dynamics and properties of T cells specific for human immunodeficiency virus (HIV), cytomegalovirus (CMV), and Epstein-Barr virus (EBV) in HIV infection were investigated in relation to...

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PMID: 15507395
DOI: 10.1016/j.clim.2004.08.002

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