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Article

HIV-1 specific CD8+ T cells with an effector phenotype and control of viral replication.

Lancet (London, England) - 13 Mar 2004

Hess Christoph, Altfeld Marcus, Thomas Seddon Y, Addo Marylyn M, Rosenberg Eric S, Allen Todd M, Draenert Rika, Eldrige Robert L, van Lunzen Jan, Stellbrink Hans-J, Walker Bruce D, Luster Andrew D

Abstract excerpt

Most people infected with HIV-1 cannot control viral replication despite the presence of virus-specific CD8+ T cells. It has been postulated that this inability is related to the failure of these cells to mature into fully differentiated effector cells. We tested this hypothesis by comparing the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15031033
DOI: 10.1016/S0140-6736(04)15735-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15031033-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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