Article
IDDM1 and multiple family history of type 1 diabetes combine to identify neonates at high risk for type 1 diabetes.
Diabetes care - 1 Nov 2004
Bonifacio Ezio, Hummel Michael, Walter Markus, Schmid Sandra, Ziegler Anette-G
Abstract excerpt
OBJECTIVE: Children of affected probands are at increased risk for type 1 diabetes. The objective of this study was to determine and stratify the risk for islet autoimmunity and childhood diabetes in newborn offspring of affected parents using family history and HLA genetic markers. RESEARCH DESIGN AND METHODS: Antibodies to islet autoantigens were measured at ages 9 months, 2 years, 5 years, and 8 years in 1,610...
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