Article
Early expression and high prevalence of islet autoantibodies for DR3/4 heterozygous and DR4/4 homozygous offspring of parents with Type I diabetes: the German BABYDIAB study.
Diabetologia - 1 Jun 1999
Schenker M, Hummel M, Ferber K, Walter M, Keller E, Albert E D, Janka H U, Kastendiek C, Sorger M, Louwen F, Ziegler A G
Abstract excerpt
AIMS/HYPOTHESIS: Islet autoantibodies precede the clinical onset of Type I (insulin-dependent) diabetes mellitus. The cumulative development of such autoantibodies in infants followed from birth and in particular infants with high-risk HLA genotypes is poorly defined, but such information is essential to design trials to prevent islet autoimmunity. METHODS: HLA genotypes were determined in offspring of parents...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.