Article
HbA1c Predicts Time to Diagnosis of Type 1 Diabetes in Children at Risk.
Diabetes - 1 May 2015
Helminen Olli, Aspholm Susanna, Pokka Tytti, Hautakangas Milla-Riikka, Haatanen Nora, Lempainen Johanna, Ilonen Jorma, Simell Olli, Knip Mikael, Veijola Riitta
Abstract excerpt
Prediction of type 1 diabetes is based on the detection of multiple islet autoantibodies in subjects who are at increased genetic risk. Prediction of the timing of diagnosis is challenging, however. We assessed the utility of HbA1c levels in predicting the clinical disease in genetically predisposed children with multiple autoantibodies. Cord blood samples from 168,055 newborn infants were screened for class II...
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